Which particle size guideline must be followed for MAA?

For the preparation of Microaggregated Albumin (MAA) used in certain diagnostic and therapeutic applications, the guideline stipulates that no particles should exceed 90 microns in diameter. This specific size limitation is crucial as particles larger than this threshold may cause blockage in the capillary beds of the lungs when administered, which can lead to complications or inaccuracies in the imaging process. Ensuring the size of the particles adheres to this guideline optimizes their distribution in the target area, allowing for effective localization and imaging of vascular abnormalities.

While other size specifications are important in different contexts within radiopharmacy, none of them align with the established protocol for MAA, thus highlighting the importance of this specific size restriction for patient safety and procedural accuracy.